Publications
Contractor Lab Publications
2022
- Intersectional mapping of multi-transmitter neurons and other cell types in the brain Cell Reports [Full Paper]
Jian Xu, Andrew Jo, Raina P DeVries, Sercan Deniz, Suraj Cherian, Idris Sunmola, Xingqi Song, John J Marshall, Katherine A Gruner, Tanya L Daigle, Anis Contractor, Talia N Lerner, Hongkui Zeng, Yongling Zhu
2021
- Kainate receptors regulate the functional properties of young adult-born dentate granule cells. Cell Reports [Full Paper]
Zhu, Y., Armstrong, J.A., Contractor, A.
- Cortical interneurons in autism. Nature Neuroscience [Full Paper]
Contractor, A., Ethell, I.M., Portera-Cailliau, C.
- Genetic disruption of Grm5 causes complex alterations in motor activity, anxiety and social behaviors. Behavioural Brain Research [Full Paper]
Xu J., Marshall J.J., Kraniotis S., Nomura T., Zhu, Y., Contractor, A.
- Pulse-Chase Proteomics of the App Knockin Mouse Models of Alzheimer’s Disease Reveals that Synaptic Dysfunction Originates in Presynaptic Terminals. Cell Systems [Full Paper]
Hark T.J., Rao N.R., Castillon C., Basta T., Smukowski S., Bao H., Upadhyay A., Bomba-Warczak E., Nomura T., O’Toole E.T., Morgan G.P., Ali L., Saito T., Guillermier C., Saido T.C., Steinhauser M.L., Stowell M.H.B., Chapman E.R., Contractor A., Savas J.N.
2020
- Recruitment of parvalbumin and somatostatin interneuron inputs to adult born dentate granule neurons. Scientific Reports [Full Paper]
Remmers, C.L., Castillion, C.C.M., Armstrong, J.N., Contractor, A.
- Neuronal BIN1 regulates presynaptic neurotransmitter release and memory consolidation. Cell Reports [Full Paper]
De Rossi, P., Nomura, T., Andrew, R.J., Masse, N., Sampathkumar, V., Musial, T., Sudwarts, A. Recupero A.J., Le Metayer, T., Hansen, M., Shim, H.N., Krause, S., Freedman, D.J., Bindokas, V., Kasthuri, N., Nicholson, D.A., Contractor, A., Thinakaran, G.
2019
- Activating newborn neurons suppresses depression and anxiety-like behaviors. Nat Comms [Full Paper]
Tunc-Ozan, E., Peng, C-Y., Zhu, Y., Dunlop, S., Contractor, A., Kessler, J.A
- Potentiating α2 subunit containing perisomatic GABAA receptors protects against seizures in a mouse model of Dravet syndrome. The Journal of Physiology [Full Paper]
Nomura T, Hawkins NA, Kearney JA, George AL Jr, Contractor A.
2018
- Critical Period Inhibition of NKCC1 Rectifies Synapse Plasticity in the Somatosensory cortex and Restores Adult Tactile Response Maps in Fragile X Mice. Molecular Psychiatry [Full Paper]
He Q., Arroya E., Smukowski, S.N., Xu, J., Piochon C., Savas, J.N., Portera-Cailliau, C. & Contractor, A.
- Development of GABAergic Inputs Is Not Altered in Early Maturation of Adult Born Dentate Granule Neurons in Fragile X Mice. eNeuro [Full Paper]
Remmers, CL & Contractor, A.
- Axonal organization defects in the hippocampus of adult conditional BACE1 knockout mice. Science Translational Medicine [Full Paper]
Ou-Yang M., Kurz J., Nomura T., Popovic J., Rajapaksha T.W., Dong H., Contractor, A., Chetkovich DM., Tourtellotte W.G. & Vassar R.
- Kainate receptors inhibit glutamate release via mobilization of endocannabinoids in striatal direct pathway Spiny Projection Neurons (dSPNs). The Journal of Neuroscience [Full Paper]
Marshall, J.J., Xu, J. & Contractor, A.
- Development of photoactivatable drugs enables nicotinic optopharmacology. Nature Methods [Full Paper]
Banala, S., Arvin, M.C., Bannon, N.M., Xiao-Tao, J. Wang, Y., Zhao, G., Marsall, J.J., Gee, K.R., Wokosin, D.L., Contractor, A., Lester, H.A., Kozorovitskiy, Y., Drenan, R.M. & Lavis L.D.
2017
- Delayed maturation of fast-spiking interneurons is rectified by activation of TrkB receptor in the mouse model of Fragile X syndrome. The Journal of Neuroscience [Full Paper]
Nomura, T., Marshall, J.J., Zhu, Y., Remmers, C.L., Xu, J., & Contractor, A
- Aberrant Rac1-cofilin signaling mediates defects in dendritic spines, synaptic function, and sensory perception in fragile X syndrome. Science Signaling [Full Paper]
Pyronneau, A., He, Q., Hwang, J.Y., Porch, M., Contractor, A. & Zukin, R.S.
- Complete Disruption of the Kainate Receptor Gene Family Results in Corticostriatal Dysfunction in Mice. Cell Reports [Full Paper]
Xu J, Marshall JJ, Fernandes HB, Nomura T, Copits BA, Procissi D, Mori S, Wang L, Zhu Y, Swanson GT, Contractor A
2016
- Distinct Subunit Domains Govern Synaptic Stability and Specificity of the Kainate Receptor. Cell Reports [Full Paper]
Straub C, Noam Y, Nomura T, Yamasaki M, Procissi D, Yan D, Fernandes HB, Zhang P, Howe JR, Watanabe M, Contractor A, Tomita S
- Subchronic phencyclidine treatment in adult mice increases GABAergic transmission and LTP threshold in the hippocampus. Neuropharmacology [Full Paper]
Nomura T, Oyamada Y, Fernandes HB, Remmers C, Xu J, Meltzer H, Contractor A
- Chronic nicotine mitigates aberrant motor learning by motor experience under dopamine deficiency. The Journal of Neuroscience [Full Paper]
Koranda, J.L., Krok, A.C., Xu, J., Contractor, A., McGehee, D.S., Beeler, J.A. & Zhuang, X.
2015
Review: Altered Neuronal and Circuit Excitability in Fragile X Syndrome. Neuron [Full Paper]
Contractor A, Klyachko VA, Portera-Cailliau C
Epac2 mediates cAMP-dependant potentiation of neurotransmission in the hippocampus. The Journal of Neuroscience [Full Paper]
Fernandes HB, Riordan S, Nomura T, Remmers CL, Kraniotis SA, Marshall JJ, Kukreja L, Vassar R, Contractor A
Double dissociation of the roles of metabotropic glutamate receptor 5 and oxytocin receptor in discrete social behaviors. Neuropsychopharmacology [Full Paper]
Mesic, I., Guzman, Y.F., Gueda, A.L., Jovasevic, V., Corcoran, K.A., Leaderbrand, K. Nishimori, K., Contractor, A., & Radulovic, J.